Life in a tight spot: Spying on bacteria in complex spaces Location: 135 Shillman Hall Abstract: Nucleic acids are programmable biomolecules that hold great promises as a therapeutic. However, with over 40 years of development, only a handful of nucleic acid drugs ever reached the market. The lack of greater success is in part due […]
Developing tools for single-molecule sequencing and imaging of RNA modifications Location: 135 Shillman Hall Abstract: Despite every cell in the human body having the same genetic makeup, gene expression varies greatly between them. The process of DNA transcription into RNA, along with subsequent post-transcriptional modifications, is crucial for achieving this variability and enabling cell specialization. […]
Name: Yuan Li Title: Establishing a Physiologically Relevant Upper Gastrointestinal In Vitro Model Incorporating Bile Salts and Simplified Commensal Microbial Consortium Date: 12/13/2024 Time: 2:00:00 PM Committee Members: Prof. Rebecca Carrier (Advisor) Prof. Abigail Koppes Prof. Erel Levine Prof. Jiahe Li Location: EXP 610-A Abstract: Bacteria-epithelial-immune crosstalk plays crucial roles in intestinal physiology. Bile salts (BS) […]