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SUMMARY:Chemical Engineering Spring Seminar Series: Dr. Sindia M. Rivera Jiménez
DESCRIPTION:Professional Organizations and Social Responsibility in Chemical Engineering Education \nProfessional organizations (POs) are established communities that significantly influence the competencies and values of engineers\, but the impact of their interaction with academia on undergraduate education is not fully understood. This study addresses this gap by exploring how engineering faculty in POs strategically incorporate social responsibility into their teaching. Relying on Paulo Freire’s critical consciousness and the Transformational Agency framework\, it examines faculty reflections on societal and power dynamics for curriculum change. \nConducted over eight months\, the study focuses on a Community of Practice (CoP) within the American Institute of Chemical Engineering’s Education Division\, engaging faculty from multiple institutions. We employed qualitative methods\, analyzing interview data through thematic analysis with In-Vivo and Axial coding. Preliminary results highlight how the CoP influences faculty’s reflective practices and understanding of societal structures\, suggesting it enhances educators’ critical awareness and ability to integrate social responsibility into their teaching. \nThe findings deepen our understanding of POs’ role in evolving engineering education. They showcase how educators’ involvement in POs can shape socially responsible engineers\, addressing the complex societal roles engineers face. This seminar aims to inspire educators with strategies for creating transformative learning environments. \n\nDr. Rivera-Jiménez is an Assistant Professor in the Department of Engineering Education at the University of Florida and is affiliated with the Department of Chemical Engineering and the Institute of Higher Education. Her research group focuses on community-driven methods to improve practices and policies that enhance the professional formation of engineers and impact the success of diverse engineering communities\, including faculty\, undergraduate and graduate students\, and transfer students. Current projects include faculty support via professional societies\, student motivation and emotions in blended learning\, and studying diverse transfer student success within organizational contexts. \nAdditionally\, she hosts “The Engineering Professor Speaks Education Podcast\,” a bilingual series exploring the nuances of being an effective engineering educator. Her most recent accolades include the AIChE IDEAL Star Award (2021)\, the AIChE Education Division Service Award (2022)\, and the ASEE Education Research Methods Apprentice Faculty Grantee Award (2023).
URL:https://che.northeastern.edu/event/chemical-engineering-spring-seminar-series-dr-sindia-m-rivera-jimenez/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
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DTSTART;TZID=America/New_York:20240408T141500
DTEND;TZID=America/New_York:20240408T143000
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SUMMARY:Soft Matter Days
DESCRIPTION:Soft Matter Days: April 8-17\, will feature invited guest speakers discussing a variety of interdisciplinary topics in soft matter and complex fluids.  These topics sit at the interface of chemical & mechanical engineering\, materials science\, physics\, chemistry\, and biology.  Guest speakers will discuss real-world phenomena found in food\, blood flow\, and granular materials.  Two talks are guest lectures in CHME5179: RSVP required for those not in the class. \nMonday\, April 8\, 2:15pm\, Curry 340\nCapillary Rise and Thin Films Near Edges: New Insights from Self-similarity\nHoward Stone\, Princeton University\nHost: Xiaoyu Tang x.tang@northeastern.edu \nTuesday\, April 9\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\n“Complex Fluids & Soft Matter in Food”\nDave Weitz\, Harvard University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nThursday\, April 11\, 1:30pm\, HS 210\nDynamics of blood flow at the cellular level in health and disease\nMichael Graham\, University of Wisconsin\nHost: Sara Hashmi s.hashmi@northeastern.edu \nFriday\, April 12\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\nNonlinear Rheology of Complex Fluids: Exploring Microstructure\nKate Honda\, Northeastern University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nWednesday\,  April 17\, 1:30pm\, HS 210\nUniversality and scaling in shear thickening suspensions\nBulbul Chakraborty\, Brandeis University\nHost: Sara Hashmi s.hashmi@northeastern.edu
URL:https://che.northeastern.edu/event/soft-matter-days/2024-04-08/
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DTSTART;TZID=America/New_York:20240410T120000
DTEND;TZID=America/New_York:20240410T130000
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SUMMARY:Chemical Engineering Spring Seminar Series: Dr. Jodie Lutkenhaus
DESCRIPTION:Organic Batteries for a More Sustainable Future \nCobalt\, nickel\, and lithium are essential ingredients in today’s lithium-ion batteries (LIBs)\, but their continued use presents economic\, ethical\, and environmental challenges. Society must now begin to consider the implications of a LIB’s full life cycle\, including the carbon footprint\, the economic and environmental costs\, and material access. These challenges motivate the case for degradable or recyclable batteries sourced from earth-abundant materials whose life cycle bears minimal impact on the environment. This presentation considers organic polymer-based batteries\, which have the potential to address many of these issues. Redox-active polymers form the positive and negative electrodes\, storing charge through a reversible redox mechanism. We demonstrate polypeptide radical batteries that degrade on command into amino acids and by-products as a first step toward circular organic batteries. Further\, we show the recycling of redox-active polymer electrodes using a solvent-based approach. Polymer-air batteries are examined as high-capacity alternatives to metal-air batteries. The molecular mechanism for each case is investigated\, revealing pathways forward for improving each polymer’s performance. Taken together\, organic batteries offer the promise of a circular platform free of critical elements. \n\nJodie L. Lutkenhaus is a Professor\, Associated Department Head\, and holder of the Axalta Chair in the Artie McFerrin Department of Chemical Engineering at Texas A&M University. Lutkenhaus received her B.S. in 2002 from The University of Texas at Austin and her Ph.D in 2007 from the Massachusetts Institute of Technology. Current research areas include polyelectrolytes\, redox-active polymers\, energy storage\, and composites. She has received recognitions including World Economic Forum Young Scientist\, Kavli Fellow\, NSF CAREER\, AFOSR Young Investigator\, and the 3M Non-tenured Faculty Award. She is the past-Chair of the AICHE Materials Engineering & Sciences Division. Lutkenhaus is the Deputy Editor of ACS Applied Polymer Materials and a member of the U.S. National Academies Board of Chemical Sciences & Technology.
URL:https://che.northeastern.edu/event/chemical-engineering-spring-seminar-series-dr-jodie-lutkenhaus/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
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DTSTART;TZID=America/New_York:20240426T120000
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SUMMARY:Chemical Engineering Spring Seminar Series: Dr. David Brayden
DESCRIPTION:Oral administration of peptides: The quest to improve bioavailability \nThe oral administration of peptides and proteins remains one of the great challenges in pharmaceutical science. Efficacy depends on patients committing to take essential medicines and this is built upon the convenience of a dosing regimen using a patient-friendly route of administration. Large molecules have problems negotiating the GI tract to achieve systemic delivery due to instability against metabolizing enzymes and low permeability across the epithelium. To date\, just five linear peptides aimed at systemic delivery have been approved by the FDA\, the most recent being oral semaglutide (Rybelsus®\, Novo Nordisk\, 2019) and oral octreotide (Mycappsa®\, Chiasma Ltd\, 2020). These approvals heralded a renewed interest in the field\, built around developing Glucagon-1-like peptide 1 (GLP-1) mimetics for Type II diabetes and obesity\, alone or as a dual agonist with other gut peptides. Relative success to date for oral peptides has been achieved with standard oral dosage forms made with permeation enhancers\, but these will only work for niche peptides with high potency and long half-lives. \nMy group has been working on the mechanism of action of the intestinal permeation enhancers that typically are used to enable these formulations\, albeit that oral bioavailability with the above products is less than 1%. We have focussed on comparisons between sodium caprate and SNAC\, both medium-chain fatty acid derivatives\, and found that they have multimodal actions suggesting a dual effects on tight junctions and the intestinal epithelial plasma membrane depending on the concentration and the bioassay. We also have contributed to the search for other permeation enhancers (alone and combination) that can be used with peptides in oral dosage forms including the Gattefosse excipients\, Labrasol® and Labrafac™. We are working on a nanotechnology concept\, where we have achieved 7% bioavailability for insulin in a rat model using a core-shell construct based on silica coating over a core of peptide and the excipients\, L-arginine\, and zinc. Finally\, devices may eventually be able to increase the oral bioavailability of peptides by an order of magnitude over permeation enhancers according to data from animal models\, but clinical testing is at an early stage and the toxicology and the regulatory pathway for these types of technologies have yet to be addressed. I will touch on aspects and examples of these multiple approaches in my talk at Northeastern. \n\nDavid Brayden is Full Professor of Advanced Drug Delivery at the School of Veterinary Medicine and a Fellow of the UCD Conway Institute. Following a Ph.D. in Pharmacology at the University of Cambridge\, UK (1989)\, and a post-doctoral research fellowship at Stanford University\, CA (1991)\, he set up Elan Corporation’s pharmacology laboratory in Dublin (1991). At Elan\, he became a senior scientist and project manager of several of Elan’s Joint-Venture drug delivery research collaborations with US biotech companies. In 2001\, he joined UCD as a college lecturer in veterinary pharmacology and was appointed Senior Lecturer (2005)\, Associate Professor (2006)\, and Full Professor (2014). He completed a successful Principle Investigator Grant from SFI on the topic of oral delivery of novel mucoadhesive polymeric peptide conjugates (2005-2009). Professor Brayden was the Director of an SFI Research Cluster grant (The Irish Drug Delivery Research Network)\, that was awarded 7.2 million euro by SFI from 2007-2013. He was the Deputy Coordinator of an EU 7th Framework grant on oral nanomedicines (www.TRANS-INT.eu)\, 2012-2017. In 2014\, he was one of four Principal Investigators (Co-PIs) on the successful SFI Centre bid in Medical Devices (CURAM)\, worth over 40 million EUR over 6 years\, which was renewed for 6 years in 2021. He is the coordinator of the Horizon Europe consortium grant\, BUCCAL-PEP\, which was awarded 4m EUR and runs from 2022-2026. He is the author or co-author of more than 300 research publications and patents. Professor Brayden serves on the Editorial Advisory Boards of Drug Discovery Today\, Advanced Drug Delivery Reviews and the Journal of Veterinary Pharmacology and Therapeutics. In 2021 he was appointed Chief Editor of “Frontiers in Drug Delivery”. He was Chairman of the UK-Ireland Chapter of the Controlled Release Society (2003-2006)\, Co-Chair of the Veterinary Programmes at the CRS international conferences (2003-2006)\, and served on the CRS Board of Scientific Advisors (2006-2009) and the CRS Annual Meeting Programme Committee (2015\, 2016). At UCD\, he was Chairman of the Animal Research Ethics Committee (2005-2007) and was a member of the UCD Research Ethics Committee (2006-2011) and was elected by Academic Council to the UCD Promotions and Tenure Committee (2010-2012) and to the UCD Academic Council for Academic Centres Committee\, ACCAC (2019-). He was Director of Research for the School of Agriculture\, Food Science and Veterinary Medicine (2007-2008) and Head of the Veterinary Biosciences Section from 2013-2017. On the teaching side\, he coordinates undergraduate and postgraduate modules on Biological Fluids and Drug Discovery and Development and contributes to a module on Cell Communication. He contributes Professional Ethics material to the Conway Institute Core Research Skills modules and also coordinates a 4th level online module on Drug Discovery and Development. In 2015\, he was made an Adjunct Professor at NUI Galway to support his Co-PI role in the SFI CURAM Centre. He was elected as a Fellow of both the Controlled Release Society (2012) and the American Association of Pharmaceutical Scientists (2017). In 2021\, he was appointed by the Minister of Health to the National Research Ethics Committee (Clinical Trials A). He acts as a consultant to selected Pharma and Biotech companies.
URL:https://che.northeastern.edu/event/chemical-engineering-spring-seminar-series-dr-david-brayden/
LOCATION:024 East Village\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
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